SCHEMBL24648581

SCHEMBL24648581

CCCc1cc(C(=O)c2ccc(-c3ccccc3)cc2)ccc1OCCBr

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARG P37231 13/20 0.54
PPARA Q07869 12/20 0.54
LTB4R Q15722 1/20 0.51
PPARD Q03181 5/20 0.50
MCHR1 Q99705 1/20 0.46
ELANE P08246 2/20 0.44
PTPN11 Q06124 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24648565 0.94 PPARG (0.56) PPARGPPARALTB4RPPARDMCHR1
SCHEMBL30020306 0.94 PPARG (0.56) PPARGPPARALTB4RPPARDMCHR1
SCHEMBL24648593 0.85 PPARG (0.57) PPARGPPARALTB4RPPARD
SCHEMBL24648542 0.84 CYP1A2 (0.52) PPARGPPARAELANE
SCHEMBL30021104 0.80 PPARG (0.59) PPARGPPARALTB4RPPARD
SCHEMBL24648603 0.80 PPARG (0.59) PPARGPPARALTB4RPPARD
SCHEMBL24648579 0.77 F10 (0.48) PPARGPPARA
SCHEMBL6936861 0.76 PPARA (0.59) PPARGPPARALTB4RPPARD
SCHEMBL6938382 0.75 PPARG (0.64) PPARGPPARALTB4RPPARDELANE
SCHEMBL10927028 0.75 SMN1; SMN2 (0.53) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022221960-A1 COMPOUNDS FOR TREATING PROLIFERATOR-ACTIVATED RECEPTORS (PPAR) MEDIATED DISEASES OR CONDITIONS Medipure Pharmaceuticals Inc. (CA) 2022-10-27 WO disclosed