Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25982118 | 0.86 | LMNA (0.41) | PIK3CAPIK3CDLMNAMAPTALDH1A1 | |
| SCHEMBL30708392 | 0.84 | LMNA (0.39) | PIK3CAPIK3CDLMNAMAPTALDH1A1 | |
| SCHEMBL30708395 | 0.81 | PIK3CD (0.43) | PIK3CAPIK3CDLMNAMAPTALDH1A1 | |
| SCHEMBL21733449 | 0.81 | LMNA (0.37) | PIK3CAPIK3CDLMNAMAPTALDH1A1 | |
| SCHEMBL29384926 | 0.81 | LMNA (0.37) | PIK3CAPIK3CDLMNAMAPTALDH1A1 | |
| SCHEMBL30708390 | 0.81 | LMNA (0.43) | PIK3CALMNAMAPTALDH1A1MEN1 | |
| SCHEMBL31234710 | 0.81 | PIK3CD (0.39) | PIK3CAPIK3CDLMNAMAPTALDH1A1 | |
| SCHEMBL30708452 | 0.80 | PDE2A (0.36) | PIK3CAPIK3CDLMNAMAPTALDH1A1 | |
| SCHEMBL22029147 | 0.79 | PIK3CD (0.42) | PIK3CAPIK3CDLMNAMAPTALDH1A1 | |
| SCHEMBL23974786 | 0.79 | PIK3CD (0.42) | PIK3CAPIK3CDLMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042919-A1 | TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2025-02-06 | — | — | US | disclosed |
| EP-4291563-A1 | TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | Genentech, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-116867792-A | Tetraepoxyazepine compound and use thereof | 基因泰克公司 | 2023-10-10 | — | — | CN | disclosed |
| US-20220281893-A1 | TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2022-09-08 | — | — | US | disclosed |
| WO-2022173678-A1 | TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281893-A1 | TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | OXA1L, CACNA1I, GRIK5 | PIK3CA 1315/4885PIK3CD 1545/4885LMNA 3975/4885 |
| US-20250042919-A1 | TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | OXA1L, CACNA1I, GRIK5 | PIK3CA 1315/4885PIK3CD 1545/4885LMNA 3975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.