Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | ACAT2 | Q9BWD1 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | FER | P16591 | 1/20 | 0.30 |
| ▸ | LTK | P29376 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17350152 | 0.74 | PDE7A (0.42) | PDE7AGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL19225163 | 0.67 | PDE7A (0.47) | PDE7AACAT2GAAKDM4EALDH1A1 | |
| SCHEMBL10758073 | 0.65 | PDE7A (0.54) | PDE7AACAT2GAAKDM4EALDH1A1 | |
| SCHEMBL23591435 | 0.65 | BACE1 (0.44) | PDE7AGAAMAPTALDH1A1MEN1 | |
| SCHEMBL6878925 | 0.65 | NOX1 (0.42) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL30552386 | 0.64 | BACE1 (0.47) | PDE7AACAT2GAAALDH1A1MEN1 | |
| SCHEMBL11536434 | 0.64 | MAOA (0.47) | PDE7AKDM4EALDH1A1RXFP1MAOA | |
| SCHEMBL624418 | 0.63 | GAA (0.59) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL29369547 | 0.63 | GAA (0.59) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL76607 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022222995-A1 | PICOLINAMIDE COMPOUND | 南京明德新药研发有限公司 | 2022-10-27 | — | — | WO | disclosed |