Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305655 | 0.73 | BRD4 (0.60) | BRD4PDE3BPDE3APDK2P2RY12 | |
| Hydrochloric Acid SCHEMBL9304134 | 0.73 | BRD4 (0.58) | BRD4PDE3BPDE3APDK2P2RY12 | |
| SCHEMBL7510947 | 0.71 | NQO2 (0.41) | PDK2L3MBTL1PPARD | |
| SCHEMBL6395807 | 0.71 | NQO2 (0.41) | PDK2L3MBTL1PPARD | |
| SCHEMBL6395808 | 0.71 | NQO2 (0.41) | PDK2L3MBTL1PPARD | |
| SCHEMBL6395804 | 0.71 | NQO2 (0.41) | PDK2L3MBTL1PPARD | |
| SCHEMBL9305716 | 0.70 | BRD4 (0.56) | BRD4PDE3BPDE3APDK2P2RY12 | |
| SCHEMBL13256061 | 0.70 | NAMPT (0.41) | BRD4MAPK1CYSLTR2CYSLTR1 | |
| Hydrochloric Acid SCHEMBL9305103 | 0.70 | BRD4 (0.55) | BRD4PDE3BPDE3APDK2P2RY12 | |
| SCHEMBL9303733 | 0.70 | BRD4 (0.55) | BRD4PDE3BPDE3APDK2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |