Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9304134 | 0.99 | BRD4 (0.58) | BRD4ACHEDRD2DRD3PDE3B | |
| SCHEMBL9305716 | 0.97 | BRD4 (0.56) | BRD4ACHEDRD2DRD3PDE3B | |
| Hydrochloric Acid SCHEMBL9305103 | 0.95 | BRD4 (0.55) | BRD4ACHEDRD2DRD3PDE3B | |
| SCHEMBL9303733 | 0.95 | BRD4 (0.55) | BRD4ACHEDRD2DRD3PDE3B | |
| Hydrochloric Acid SCHEMBL9306210 | 0.94 | BRD4 (0.54) | BRD4ACHEDRD2DRD3PDE3B | |
| SCHEMBL5681817 | 0.88 | ACHE (0.58) | BRD4ACHEDRD2DRD3 | |
| SCHEMBL9518883 | 0.88 | ACHE (0.58) | BRD4ACHEDRD2DRD3 | |
| SCHEMBL5679478 | 0.88 | ACHE (0.58) | BRD4ACHEDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8765229 | 0.87 | ACHE (0.57) | BRD4ACHEDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9443687 | 0.87 | ACHE (0.57) | BRD4ACHEDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312961-A | 2-amino-7-hydroxytetralin carboxylalkyl ethers | ELF SANOFI (FR) | 1994-05-17 | — | — | US | claimed |
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | claimed |
| US-5312961-A | 2-amino-7-hydroxytetralin carboxylalkyl ethers | ELF SANOFI (FR) | 1994-05-17 | — | — | US | disclosed |