Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 10/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | SIK1 | P57059 | 1/20 | 0.48 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | DSTYK | Q6XUX3 | 1/20 | 0.48 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 6/20 | 0.48 |
| ▸ | ABL1 | P00519 | 5/20 | 0.48 |
| ▸ | ABL2 | P42684 | 5/20 | 0.48 |
| ▸ | FGR | P09769 | 1/20 | 0.46 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.46 |
| ▸ | TXK | P42681 | 1/20 | 0.46 |
| ▸ | FRK | P42685 | 1/20 | 0.46 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30120822 | 1.00 | SRC (0.53) | SRCRIPK2PDGFRBKITFLT3 | |
| SCHEMBL30120922 | 0.88 | SRC (0.53) | SRCRIPK2PDGFRBKITFLT3 | |
| SCHEMBL24651194 | 0.88 | SRC (0.53) | SRCRIPK2PDGFRBKITFLT3 | |
| SCHEMBL27889174 | 0.84 | EIF2AK3 (0.40) | SRCRIPK1LCKTEKRET | |
| Hydrochloric Acid SCHEMBL868325 | 0.83 | EIF2AK3 (0.39) | SRCRIPK1LCKTEKRET | |
| SCHEMBL30120733 | 0.81 | EIF2AK3 (0.51) | SRCRIPK2PDGFRBKITFLT3 | |
| SCHEMBL24650666 | 0.81 | EIF2AK3 (0.51) | SRCRIPK2PDGFRBKITFLT3 | |
| SCHEMBL24650649 | 0.80 | KDR (0.50) | SRCEGFRABL1RET | |
| SCHEMBL30120839 | 0.80 | KDR (0.50) | SRCEGFRABL1RET | |
| SCHEMBL24651165 | 0.74 | KDR (0.49) | SRCEGFRABL1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |