Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.51 |
| ▸ | SRC | P12931 | 10/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 7/20 | 0.48 |
| ▸ | KIT | P10721 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | SIK1 | P57059 | 1/20 | 0.48 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | DSTYK | Q6XUX3 | 1/20 | 0.48 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 6/20 | 0.45 |
| ▸ | ABL1 | P00519 | 5/20 | 0.45 |
| ▸ | ABL2 | P42684 | 4/20 | 0.45 |
| ▸ | AXL | P30530 | 2/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650666 | 1.00 | EIF2AK3 (0.51) | EIF2AK3SRCRIPK2KITFLT3 | |
| SCHEMBL24651194 | 0.92 | SRC (0.53) | SRCRIPK2KITFLT3PDGFRB | |
| SCHEMBL30120922 | 0.92 | SRC (0.53) | SRCRIPK2KITFLT3PDGFRB | |
| SCHEMBL869108 | 0.83 | EIF2AK3 (0.49) | EIF2AK3RIPK1 | |
| SCHEMBL29911812 | 0.83 | EIF2AK3 (0.49) | EIF2AK3RIPK1 | |
| Hydrochloric Acid SCHEMBL868686 | 0.82 | EIF2AK3 (0.48) | EIF2AK3RIPK1 | |
| Hydrochloric Acid SCHEMBL23042914 | 0.82 | EIF2AK3 (0.48) | EIF2AK3RIPK1 | |
| SCHEMBL24650658 | 0.81 | SRC (0.53) | SRCRIPK2KITFLT3PDGFRB | |
| SCHEMBL30120822 | 0.81 | SRC (0.53) | SRCRIPK2KITFLT3PDGFRB | |
| SCHEMBL19743545 | 0.79 | EIF2AK3 (0.63) | EIF2AK3SRCRIPK2KITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |