SCHEMBL24651058 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	PIK3CD	O00329	14/20	0.56

▸	KDR	P35968	13/20	0.56

▸	ABL1	P00519	12/20	0.56

▸	EGFR	P00533	12/20	0.56

▸	HCK	P08631	12/20	0.56

▸	SRC	P12931	12/20	0.56

▸	PIK3CA	P42336	12/20	0.56

▸	PIK3CB	P42338	12/20	0.56

▸	MTOR	P42345	12/20	0.56

▸	PIK3CG	P48736	12/20	0.56

▸	EPHB4	P54760	12/20	0.56

▸	PRKDC	P78527	12/20	0.56

▸	PI4KB	Q9UBF8	8/20	0.56

▸	BTK	Q06187	5/20	0.47

▸	EIF2AK3	Q9NZJ5	2/20	0.45

▸	RET	P07949	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30120806	1.00	PIK3CD (0.56)	PIK3CDKDRABL1EGFRHCK
SCHEMBL24651055	0.93	PIK3CD (0.52)	PIK3CDKDRABL1EGFRHCK
SCHEMBL30120913	0.93	PIK3CD (0.52)	PIK3CDKDRABL1EGFRHCK
SCHEMBL30120847	0.91	PIK3CD (0.48)	PIK3CDKDRABL1EGFRHCK
SCHEMBL24651164	0.91	PIK3CD (0.48)	PIK3CDKDRABL1EGFRHCK
SCHEMBL24650649	0.88	KDR (0.50)	PIK3CDKDRABL1EGFRHCK
SCHEMBL30120839	0.88	KDR (0.50)	PIK3CDKDRABL1EGFRHCK
SCHEMBL24651153	0.82	SRC (0.59)	PIK3CDKDRABL1EGFRHCK
SCHEMBL30120814	0.82	SRC (0.59)	PIK3CDKDRABL1EGFRHCK
SCHEMBL24651194	0.80	SRC (0.53)	ABL1EGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022212326-A1	NEK7 INHIBITORS	Halia Therapeutics, Inc. (US)	2022-10-06	—	—	WO	disclosed