Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.48 |
| ▸ | KDR | P35968 | 13/20 | 0.48 |
| ▸ | ABL1 | P00519 | 11/20 | 0.48 |
| ▸ | EGFR | P00533 | 11/20 | 0.48 |
| ▸ | HCK | P08631 | 11/20 | 0.48 |
| ▸ | SRC | P12931 | 11/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.48 |
| ▸ | MTOR | P42345 | 11/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.48 |
| ▸ | PRKDC | P78527 | 11/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 10/20 | 0.48 |
| ▸ | EPHB4 | P54760 | 10/20 | 0.48 |
| ▸ | BTK | Q06187 | 5/20 | 0.45 |
| ▸ | RET | P07949 | 3/20 | 0.43 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30120847 | 1.00 | PIK3CD (0.48) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL24651058 | 0.91 | PIK3CD (0.56) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL30120806 | 0.91 | PIK3CD (0.56) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL30120913 | 0.91 | PIK3CD (0.52) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL24651055 | 0.91 | PIK3CD (0.52) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL24651165 | 0.89 | KDR (0.49) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL30121083 | 0.89 | KDR (0.49) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL24651153 | 0.79 | SRC (0.59) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL24650649 | 0.79 | KDR (0.50) | PIK3CDKDRABL1EGFRHCK | |
| SCHEMBL30120814 | 0.79 | SRC (0.59) | PIK3CDKDRABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |