Boric Acid

Boric Acid

SCHEMBL2465381

Brc1cc(Br)c(Br)c(Br)c1Br.OB(O)O

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.48
CA4 P22748 3/20 0.48
CA1 P00915 2/20 0.48
CA6 P23280 2/20 0.48
TDP1 Q9NUW8 2/20 0.46
APEX1 P27695 1/20 0.42
AKR1B1 P15121 5/20 0.40
EIF2AK2 P19525 1/20 0.38
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
CSNK2A1 P68400 1/20 0.38
AHR P35869 2/20 0.33
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
ALOX15 P16050 3/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL356679 0.86 TDP1 (0.56) CA2CA4CA1CA6TDP1
Boric Acid SCHEMBL2459411 0.79 CA2 (0.42) CA2CA4CA1CA6APEX1
Bromomethane SCHEMBL27669607 0.79 TDP1 (0.50) CA2CA4CA1CA6TDP1
Ethylene SCHEMBL27257227 0.79 TDP1 (0.50) CA2CA4CA1CA6TDP1
Ethane SCHEMBL27516377 0.79 TDP1 (0.50) CA2CA4CA1CA6TDP1
Ethylene SCHEMBL3851523 0.79 TDP1 (0.50) CA2CA4CA1CA6TDP1
Cyanide SCHEMBL28813797 0.76 TDP1 (0.48) CA2CA4CA1CA6TDP1
Phosphoric Acid SCHEMBL10684780 0.75 CA2 (0.43) CA2CA4CA1CA6TDP1
Formic Acid SCHEMBL27460871 0.75 EIF2AK2 (0.45) CA2CA4CA1CA6TDP1
SCHEMBL9472226 0.71 CA1 (0.68) CA2CA4CA1CA6TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481327-B2 Methods for using congeneric, chlorinated, brominated and/or iodised, fluorinated aromatic standard compounds having two benzol rings CHIRON AS (NO) 2013-07-09 US disclosed
US-20110229973-A1 CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF CHIRON AS (NO) 2011-09-22 US disclosed
US-20070298501-A1 Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof CHIRON AS (NO) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298501-A1 Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof CBR1, CYP1A1, CYP1B1 CA2 988/4885CA4 445/4885CA1 1338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.