SCHEMBL24654022

SCHEMBL24654022

N#C/N=C(\NCCCN)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.38
POLB P06746 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
FURIN P09958 1/20 0.33
MGLL Q99685 2/20 0.33
RECQL P46063 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1151212 0.85 KMT2A (0.40) KMT2APOLBZDHHC2HSD17B10
SCHEMBL1151213 0.85 KMT2A (0.40) KMT2APOLBZDHHC2HSD17B10
SCHEMBL14996220 0.84 ZDHHC2 (0.50) ZDHHC2MGLL
SCHEMBL3421932 0.84 ZDHHC2 (0.50) ZDHHC2MGLL
SCHEMBL13630803 0.83 ZDHHC2 (0.52) ZDHHC2MGLL
SCHEMBL13617146 0.82 MAPT (0.40) KMT2APOLBZDHHC2MGLLRECQL
SCHEMBL29306423 0.82 SMN1; SMN2 (0.46) KMT2AL3MBTL1KDM4EHSD17B10
SCHEMBL13617147 0.81 ZDHHC2 (0.36) KMT2AL3MBTL1ZDHHC2MGLLRECQL
SCHEMBL14996210 0.81 HPGD (0.40) KMT2AL3MBTL1ZDHHC2MGLL
SCHEMBL24654021 0.80 SMN1; SMN2 (0.37) KMT2AL3MBTL1ZDHHC2MGLLRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226026-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2024-07-11 US disclosed
WO-2022204288-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2022-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226026-A1 BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PLTP, LNPK, PLIN3 KMT2A 4165/4885POLB 1805/4885L3MBTL1 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.