Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719822 | 0.87 | EPHX1 (0.50) | SPHK1EPHX1HPGDSMN1; SMN2LMNA | |
| SCHEMBL3427647 | 0.83 | SPHK1 (0.54) | SPHK1EPHX1HPGDSMN1; SMN2LMNA | |
| SCHEMBL29306462 | 0.81 | CYP3A4 (0.37) | SPHK1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL24654166 | 0.81 | CYP3A4 (0.37) | SPHK1ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL20119053 | 0.79 | EPHX1 (0.48) | SPHK1EPHX1HPGDSMN1; SMN2LMNA | |
| SCHEMBL29306660 | 0.78 | SPHK1 (0.50) | SPHK1EPHX1 | |
| SCHEMBL25564851 | 0.78 | ALDH1A1 (0.33) | ALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL1236882 | 0.78 | HPGD (0.56) | SPHK1EPHX1HPGDSMN1; SMN2LMNA | |
| SCHEMBL1236881 | 0.78 | HPGD (0.56) | SPHK1EPHX1HPGDSMN1; SMN2LMNA | |
| SCHEMBL1237682 | 0.78 | HPGD (0.56) | SPHK1EPHX1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204288-A1 | BRANCHED TAIL LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2022-09-29 | — | — | WO | disclosed |