⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228233 | 0.70 | — | — | |
| SCHEMBL19361929 | 0.69 | — | — | |
| SCHEMBL21723305 | 0.68 | — | — | |
| SCHEMBL22482851 | 0.68 | — | — | |
| SCHEMBL2638363 | 0.67 | — | — | |
| SCHEMBL14048788 | 0.65 | — | — | |
| SCHEMBL19361932 | 0.65 | — | — | |
| SCHEMBL20517721 | 0.64 | KMT2A (0.49) | — | |
| SCHEMBL4629985 | 0.63 | CYP1A2 (0.41) | — | |
| SCHEMBL22885025 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043460-A1 | ANTIPROLIFERATION COMPOUNDS AND USES THEREOF | Merck Patent GmbH (DE) | 2022-08-17 | — | — | EP | disclosed |