Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2462585 | 1.00 | CA1 (0.35) | CA1GPR84FFAR1FFAR4LMNA | |
| Acetic Acid SCHEMBL2463875 | 1.00 | CA1 (0.35) | CA1GPR84FFAR1FFAR4LMNA | |
| Acetic Acid SCHEMBL2466675 | 0.98 | CA1 (0.36) | CA1GPR84FFAR1FFAR4KDM4E | |
| Acetic Acid SCHEMBL2466591 | 0.83 | CES2 (0.44) | CA1GPR84FFAR1FFAR4ALDH1A1 | |
| Acetic Acid SCHEMBL2466806 | 0.83 | CES2 (0.44) | CA1GPR84FFAR1FFAR4ALDH1A1 | |
| Acetic Acid SCHEMBL2465384 | 0.83 | CES2 (0.44) | CA1GPR84FFAR1FFAR4ALDH1A1 | |
| Acetic Acid SCHEMBL2469511 | 0.83 | CES2 (0.44) | CA1GPR84FFAR1FFAR4ALDH1A1 | |
| Acetic Acid SCHEMBL2465729 | 0.83 | CES2 (0.44) | CA1GPR84FFAR1FFAR4ALDH1A1 | |
| Acetic Acid SCHEMBL2466008 | 0.83 | CES2 (0.44) | CA1GPR84FFAR1FFAR4ALDH1A1 | |
| Acetic Acid SCHEMBL2465467 | 0.83 | CES2 (0.44) | CA1GPR84FFAR1FFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013085-B2 | addition polymerization of ethylenically unsaturated monomers in an aqueous medium in the presence of polymer particles and at least one dispersant; polymer powders used as additives in adhesives, seals, plasters, renderings, paper coatings or paints | BASF AKTIENGESELLSCHAFT (DE) | 2011-09-06 | — | — | US | disclosed |
| US-20060264558-A1 | Method for the production of an aqueous polymer dispersion | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | US | disclosed |
| US-6852662-B2 | Catalyst systems based on transition metal complexes for carbon monoxide copolymerization in an aqueous medium | BASF AKTIENGESELLSCHAFT (DE) | 2005-02-08 | — | — | US | disclosed |
| EP-1091995-B1 | CATALYST SYSTEMS ON THE BASIS OF TRANSITION METAL COMPLEXES FOR CARBON MONOXIDE COPOLYMERISATION IN AN AQUEOUS MEDIUM | BASF AG (DE) | 2004-12-01 | — | — | EP | disclosed |
| US-20040092682-A1 | Catalyst systems based on transition metal complexes for carbon monoxide copolymerization in an aqueous medium | QUEISSER JOACHIM (DE) | 2004-05-13 | — | — | US | disclosed |
| US-6667386-B1 | Linear, alternating copolymerization of carbon monoxide and alpha-olefins in aqueous media; constantly high average catalyst activity | BASF AKTIENGESELLSCHAFT (DE) | 2003-12-23 | — | — | US | disclosed |
| US-6541564-B2 | Copolymerization of carbon monoxide and the olefinically unsaturated carried out in an aqueous medium in the presence of metal complexes, dispersant, organic hydroxy compound, wherein the soluble macromolecular host compound | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |
| US-20020198359-A1 | Priparation of copolymers of carbon monoxide and an olefinically unsaturated compound in an aqueous medium | BASF AKIENGESELLSCHAFT (DE) | 2002-12-26 | — | — | US | disclosed |
| EP-1091967-B1 | WATER-SOLUBLE TRANSITION METAL COMPLEXES | BASF AG (DE) | 2002-06-05 | — | — | EP | disclosed |