Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.48 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29834253 | 1.00 | ALDH1A1 (0.70) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL597667 | 0.91 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL988961 | 0.89 | ALDH1A1 (0.89) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL4847673 | 0.89 | ALDH1A1 (0.89) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL30484226 | 0.89 | ALDH1A1 (0.89) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL4851898 | 0.89 | ALDH1A1 (0.89) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL4852173 | 0.89 | ALDH1A1 (0.89) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL4848822 | 0.86 | ALDH1A1 (0.84) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL31326805 | 0.86 | ALDH1A1 (0.84) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 | |
| SCHEMBL1799999 | 0.86 | ALDH1A1 (0.84) | ALDH1A1HSD17B10CYP1B1HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105160-A4 | LATS KNOCK-OUT ANIMAL MODELS AND THEIR USES | UNIV YALE (US) | 2002-02-06 | — | — | EP | claimed |
| EP-1105160-A1 | LATS KNOCK-OUT ANIMAL MODELS AND THEIR USES | YALE UNIVERSITY (US) | 2001-06-13 | — | — | EP | claimed |
| EP-0777458-B1 | CONTROL OF HAIR GROWTH | UNIV SHEFFIELD (GB) | 2000-12-06 | — | — | EP | claimed |
| WO-2000010602-A9 | LATS KNOCK-OUT ANIMAL MODELS AND THEIR USES | UNIV YALE (US) | 2000-09-21 | — | — | WO | claimed |
| WO-2000010602-A1 | LATS KNOCK-OUT ANIMAL MODELS AND THEIR USES | YALE UNIVERSITY (US) | 2000-03-02 | — | — | WO | claimed |
| US-6020327-A | Control of hair growth | THE CENTRAL SHEFFIELD UNIVERSITY HOSPITALS NHS TRUST (GB) | 2000-02-01 | — | — | US | claimed |
| JP-10042875-A | — | — | None | — | — | JP | disclosed |
| US-12570718-B2 | PD-1-CD28 fusion proteins and their use in medicine | KOBOLD SEBASTIAN (DE) | 2026-03-10 | — | — | US | disclosed |
| US-20250242023-A1 | GENETICALLY ENGINEERED T CELL RECEPTORS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2025-07-31 | — | — | US | disclosed |
| EP-4349854-A2 | PD1-CD28 FUSION PROTEINS AND THEIR USE IN MEDICINE | Kobold, Sebastian (DE) | 2024-04-10 | — | — | EP | disclosed |
| US-20240052418-A1 | METHOD FOR PREDICTING A SUBJECT'S RESPONSE TO SLC MODULATOR THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-02-15 | — | — | US | disclosed |
| EP-3909972-B1 | PD1-CD28 FUSION PROTEINS AND THEIR USE IN MEDICINE | KOBOLD SEBASTIAN (DE) | 2024-02-14 | — | — | EP | disclosed |
| CN-117210480-A | Nucleotide sequences expressing exosome-anchored proteins for use as vaccines | 国家高等卫生院 | 2023-12-12 | — | — | CN | disclosed |
| EP-0007823-B1 | 3,20-DIOXO-4,9-DIENE-21-HYDROXY-STEROID COMPOUNDS, PROCESS FOR THEIR PREPARATION, THEIR USE IN MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1983-07-20 | — | — | EP | disclosed |
| EP-0046001-A1 | 3-Oxo or 3-ketal, 20-oxo-diene steroid compounds, process for their preparation and their utilization in the preparation of medicines | ROUSSEL-UCLAF (FR) | 1982-02-17 | — | — | EP | disclosed |
| US-4273771-A | ANTIESTROGENS, ANTIFERTILITY AGENTS | ROUSSEL UCLAF (FR) | 1981-06-16 | — | — | US | disclosed |
| US-4264729-A | Method and reagent for detecting cancerigenic and anticancerous substances | BELJANSKI MIRKO | 1981-04-28 | — | — | US | disclosed |
| EP-0007823-A2 | 3,20-Dioxo-4,9-diene-21-hydroxy-steroid compounds, process for their preparation, their use in medicines and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1980-02-06 | — | — | EP | disclosed |
| US-4152325-A | NOVEL STEROIDS AND THEIR USE | ROUSSEL UCLAF (FR) | 1979-05-01 | — | — | US | disclosed |
| US-4138471-A | HEAT TREATMENT IN A FLUIDIZED BED | J. M. HUBER CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570718-B2 | PD-1-CD28 fusion proteins and their use in medicine | CD4, ICOS, CD274 | ALDH1A1 4732/4885HSD17B10 4492/4885CYP1B1 4398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.