Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18516697 | 0.78 | KDM5A (0.46) | KDM5AKDM5BKDM2B | |
| SCHEMBL24925524 | 0.78 | — | — | |
| SCHEMBL2974423 | 0.77 | KDM2B (0.33) | KDM5AKDM5BKDM2BKDM4AKDM4C | |
| SCHEMBL306663 | 0.77 | KDM5A (0.44) | KDM5AKDM5BKDM2BKDM4AKDM4C | |
| SCHEMBL5199907 | 0.77 | KDM5A (0.44) | KDM5AKDM5BKDM2BKDM4AKDM4C | |
| SCHEMBL2976275 | 0.76 | CARM1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL22833798 | 0.76 | KDM5A (0.40) | KDM5AKDM5B | |
| SCHEMBL10272686 | 0.76 | KDM5A (0.43) | KDM5AKDM5BKDM2BHRH3KDM4A | |
| SCHEMBL24655835 | 0.75 | — | — | |
| SCHEMBL20757533 | 0.75 | KDM5A (0.44) | KDM5AKDM5BKDM2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234271-A1 | HETEROARYL COMPOUNDS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-11-10 | — | — | WO | disclosed |