Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 13/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18516702 | 0.82 | ALPL (0.39) | ALPLPLAAALPGQPCT | |
| SCHEMBL31251980 | 0.79 | QPCT (0.48) | ALPLPLAAALPGQPCT | |
| SCHEMBL24655834 | 0.78 | KDM5A (0.44) | KDM5AKDM5BKDM2B | |
| SCHEMBL306663 | 0.78 | KDM5A (0.44) | KDM5AKDM5BKDM2B | |
| SCHEMBL5199907 | 0.78 | KDM5A (0.44) | KDM5AKDM5BALPLPLAAALPG | |
| SCHEMBL10272686 | 0.77 | KDM5A (0.43) | KDM5AKDM5BKDM2B | |
| SCHEMBL10254506 | 0.76 | KDM5A (0.43) | KDM5AKDM5BKDM2B | |
| SCHEMBL8604979 | 0.75 | — | — | |
| SCHEMBL1178918 | 0.75 | — | — | |
| SCHEMBL24496205 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081923-A1 | PLATELET-DERIVED GROWTH FACTOR RECEPTOR (PDGFR) ALPHA INHIBITORS AND USES THEREOF | Frequency Therapeutics, Inc. (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-1957498-B1 | INHIBITORS OF VEGF RECEPTOR AND HGF RECEPTOR SIGNALING | METHYLGENE INC (CA) | 2017-02-15 | — | — | EP | disclosed |