SCHEMBL24656351

SCHEMBL24656351

CC1(C)c2ccccc2-c2cc(N(c3ccc(-c4ccc5ccccc5c4)cc3)c3ccc(-c4cc5ccc6ccccc6c5c5ccccc45)cc3)ccc21

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.34
LIPG Q9Y5X9 1/20 0.34
CHRNA1 P02708 1/20 0.30
CHRNG P07510 1/20 0.30
CHRNB1 P11230 1/20 0.30
CHRNB2 P17787 1/20 0.30
SLC6A2 P23975 1/20 0.30
CHRNB4 P30926 1/20 0.30
SLC6A4 P31645 1/20 0.30
CHRNA3 P32297 1/20 0.30
CHRNA4 P43681 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CHRND Q07001 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24656344 0.95 CHRNA1 (0.33) LPLLIPGCHRNA1CHRNGCHRNB1
SCHEMBL24657376 0.95 KDM4E (0.31)
SCHEMBL24657110 0.94 LPL (0.34) LPLLIPGCHRNA1CHRNGCHRNB1
SCHEMBL24656343 0.94 KDM4E (0.34)
SCHEMBL24656352 0.93 KDM4E (0.32)
SCHEMBL24656354 0.92 KDM4E (0.32)
SCHEMBL24656348 0.92
SCHEMBL24657371 0.92 LPL (0.34) LPLLIPGCHRNA1CHRNGCHRNB1
SCHEMBL24656346 0.92 CHRNB4 (0.33) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2
SCHEMBL24656292 0.92 LPL (0.33) LPLLIPGCHRNA1CHRNGCHRNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243100-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed