SCHEMBL24656353

SCHEMBL24656353

CC1(C)c2ccccc2-c2cc(N(c3ccc(-c4cc5ccc6ccccc6c5c5ccccc45)cc3)c3ccc4c(c3)oc3ccccc34)ccc21

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
ABCG2 Q9UNQ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24657155 0.94 TDP1 (0.31) TDP1L3MBTL1ABCG2
SCHEMBL24656355 0.94 ABCG2 (0.32) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL26060861 0.94 TDP1 (0.31) TDP1L3MBTL1KDM4EMEN1ALDH1A1
SCHEMBL24655260 0.91 HCRTR1 (0.32) TDP1L3MBTL1KDM4EMEN1ALDH1A1
SCHEMBL24656279 0.91 TDP1 (0.31) TDP1L3MBTL1KDM4EMEN1ALDH1A1
SCHEMBL26059237 0.90 PGR (0.32) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL24657376 0.90 KDM4E (0.31) L3MBTL1KDM4EMEN1ALDH1A1HPGD
SCHEMBL24657387 0.89 TDP1 (0.33) TDP1L3MBTL1KDM4EMEN1ALDH1A1
SCHEMBL24656918 0.89 TDP1 (0.34) TDP1L3MBTL1KDM4EMEN1ALDH1A1
SCHEMBL26060863 0.89 ABCG2 (0.31) TDP1L3MBTL1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243100-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed