SCHEMBL24657333

SCHEMBL24657333

N=C(/N=C(\N)c1cccc2oc3cc(-c4ccc5c(c4)oc4ccc6ccccc6c45)ccc3c12)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.35
ABCG2 Q9UNQ0 6/20 0.35
PAX8 Q06710 2/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
FYN P06241 1/20 0.35
MAPK3 P27361 1/20 0.35
AHR P35869 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPT P10636 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KLKB1 P03952 1/20 0.33
TDP1 Q9NUW8 4/20 0.33
NPC1 O15118 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
RAB9A P51151 1/20 0.33
PRSS1 P07477 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25506602 0.94 HTR2B (0.36) HTR2BABCG2PAX8CYP1A1CYP1A2
SCHEMBL25506752 0.92 HTR2B (0.37) HTR2BABCG2PAX8ALDH1A1HPGD
SCHEMBL24655489 0.91 PLAU (0.36) HTR2BCYP1A2ALDH1A1HPGDSMN1; SMN2
SCHEMBL24655499 0.91 PRSS1 (0.40) HTR2BALDH1A1MAPTKLKB1PRSS1
SCHEMBL24656629 0.90 ERBB2 (0.35) HTR2BCYP1A2FYNAHRALDH1A1
SCHEMBL25008980 0.87 WDR5 (0.40) HTR2BALDH1A1HPGDSMN1; SMN2KLKB1
SCHEMBL23822492 0.87 PLAU (0.38) HTR2BCYP1A1CYP1A2ALDH1A1MAPT
SCHEMBL25654459 0.86 HTR2B (0.36) HTR2BALDH1A1HPGDMAPTMEN1
SCHEMBL23820548 0.86 ABCG2 (0.34) HTR2BABCG2PAX8CYP1A1CYP1A2
SCHEMBL25654493 0.86 PRSS1 (0.38) HTR2BKLKB1PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed