SCHEMBL24657368

SCHEMBL24657368

c1ccc(N(c2ccc(-c3ccc4ccccc4c3)cc2)c2ccc(-c3cc4ccc5ccccc5c4c4ccccc34)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
KDM4E B2RXH2 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GPR84 Q9NQS5 3/20 0.36
GSTP1 P09211 1/20 0.36
ALOX5 P09917 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
MAPT P10636 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24657660 0.97 KDM4E (0.40) ESR1ESR2KDM4EMEN1KMT2A
SCHEMBL9888942 0.96 GPR84 (0.37) ESR1ESR2KDM4EMEN1KMT2A
SCHEMBL24656398 0.95 KDM4E (0.38) ESR1ESR2KDM4EMEN1KMT2A
SCHEMBL24657604 0.95 KDM4E (0.38) ESR1ESR2KDM4EMEN1KMT2A
SCHEMBL24657658 0.95 KDM4E (0.38) ESR1ESR2KDM4EMEN1KMT2A
SCHEMBL24656410 0.93 KDM4E (0.39) KDM4EMEN1KMT2AGPR84GSTP1
SCHEMBL24657316 0.93 KDM4E (0.43) KDM4EMEN1KMT2AGPR84CA1
SCHEMBL24656654 0.93 KDM4E (0.43) KDM4EMEN1KMT2AGPR84CA1
SCHEMBL24657659 0.93 KDM4E (0.43) KDM4EMEN1KMT2AGPR84CA1
SCHEMBL9888984 0.93 KDM4E (0.42) KDM4EMEN1KMT2AGPR84ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243100-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed