SCHEMBL24657488

SCHEMBL24657488

c1ccc2c(c1)ccc1ccc3cc(-c4ccc(N(c5ccc6c(c5)sc5ccccc56)c5ccc6oc7ccccc7c6c5)cc4)ccc3c12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ABCG2 Q9UNQ0 5/20 0.32
RAB9A P51151 3/20 0.32
NPC1 O15118 3/20 0.32
PAX8 Q06710 2/20 0.32
NQO1 P15559 1/20 0.32
NQO2 P16083 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
FYN P06241 1/20 0.32
MAPK3 P27361 1/20 0.32
AHR P35869 1/20 0.32
MAPT P10636 3/20 0.32
HPGD P15428 3/20 0.32
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24657466 0.96 TDP1 (0.34) TDP1L3MBTL1ABCG2RAB9ANPC1
SCHEMBL24655228 0.96 TDP1 (0.34) TDP1L3MBTL1ABCG2RAB9ANPC1
SCHEMBL25871848 0.94 MAPT (0.33) TDP1L3MBTL1RAB9ANPC1AHR
SCHEMBL26057192 0.94 KDM4E (0.34) TDP1L3MBTL1RAB9ANPC1MAPT
SCHEMBL24657464 0.93 TDP1 (0.33) TDP1L3MBTL1ABCG2NQO1NQO2
SCHEMBL25873365 0.93 TDP1 (0.34) TDP1L3MBTL1ABCG2RAB9ANPC1
SCHEMBL24657642 0.92 TDP1 (0.37) TDP1L3MBTL1ABCG2RAB9ANPC1
SCHEMBL24655730 0.92 TDP1 (0.34) TDP1L3MBTL1ABCG2RAB9ANPC1
SCHEMBL24655724 0.92 ABCG2 (0.32) TDP1L3MBTL1ABCG2RAB9ANPC1
SCHEMBL25883946 0.92 ALDH1A1 (0.32) RAB9ANPC1MAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243100-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed