Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL248642 | 0.99 | SLC6A4 (0.57) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL30747225 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL26989874 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL30747224 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL30747230 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL2316742 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL2316862 | 0.87 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Pudafensine SCHEMBL30747233 | 0.87 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| SCHEMBL221770 | 0.85 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3MAOBMAOA | |
| Hydrochloric Acid SCHEMBL220690 | 0.84 | SLC6A4 (0.60) | SLC6A4SLC6A2SLC6A3MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000881-A1 | CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2012-01-05 | — | — | WO | claimed |
| WO-2012000881-A1 | CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2012-01-05 | — | — | WO | disclosed |