SCHEMBL24658178

SCHEMBL24658178

CC1(C)c2ccccc2-c2c(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5c(ccc6ccc7ccccc7c65)c4)cc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.33
HSD17B2 P37059 2/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2B6 P20813 1/20 0.32
CYP2C19 P33261 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
SLC6A9 P48067 1/20 0.31
CHRNA1 P02708 2/20 0.31
CHRNG P07510 2/20 0.31
CHRNB1 P11230 2/20 0.31
CHRNB2 P17787 2/20 0.31
SLC6A2 P23975 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24658204 0.98 HSD17B1 (0.30) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL24658167 0.97 CDK4 (0.31) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL24657962 0.97 ERBB2 (0.31) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL24658207 0.96 HSD17B1 (0.33) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL24658201 0.96 CHRNA1 (0.33) ESR1ESR2CYP1A2CHRNA1CHRNG
SCHEMBL24656949 0.96 CDK4 (0.31) CYP1A2CHRNA1CHRNGCHRNB1CHRNB2
SCHEMBL24658203 0.95 CA12 (0.35) HSD17B1HSD17B2CA12CA1CA2
SCHEMBL26060643 0.95 HSD17B1 (0.33) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL24658171 0.94 CHRNA1 (0.33) CYP1A2CHRNA1CHRNGCHRNB1CHRNB2
SCHEMBL24656966 0.94 CHRNA1 (0.32) CHRNA1CHRNGCHRNB1CHRNB2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4243100-A1 ORGANIC LIGHT-EMITTING DEVICE Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed