Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.59 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.59 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.59 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL1339852 | 0.86 | — | — | |
| Chlorobenzene SCHEMBL1331798 | 0.86 | — | — | |
| Chlorobenzene SCHEMBL1568605 | 0.86 | TSHR (1.00) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| Chlorobenzene SCHEMBL11220629 | 0.86 | TSHR (1.00) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| Chlorobenzene SCHEMBL9721018 | 0.86 | TSHR (1.00) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL24715429 | 0.86 | TSHR (1.00) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| Chlorobenzene SCHEMBL1330702 | 0.86 | — | — | |
| Chlorobenzene SCHEMBL2044 | 0.86 | — | — | |
| Chlorobenzene SCHEMBL2168046 | 0.86 | TSHR (1.00) | TSHRORAI1ORAI2ORAI3TRPV6 | |
| Chlorobenzene SCHEMBL1330516 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113511970-B | Synthesis method of aryl substituted alkyne | 杭州师范大学 | 2024-04-09 | — | — | CN | claimed |
| CN-115651203-A | Supermolecular crystal framework material based on BN coordination bond and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2023-01-31 | — | — | CN | claimed |
| CN-113511970-B | Synthesis method of aryl substituted alkyne | 杭州师范大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-110291076-B | Novel heterocyclic compound and organic light-emitting element using same | 株式会社LG化学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116102390-A | Method for synthesizing biphenyl compounds by adopting micro-channel continuous flow reactor | 西安凯立新材料股份有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-115651203-A | Supermolecular crystal framework material based on BN coordination bond and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2023-01-31 | — | — | CN | disclosed |
| CN-115651203-A | Supermolecular crystal framework material based on BN coordination bond and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2023-01-31 | — | — | CN | disclosed |
| CN-115557883-A | Synthesis process of amlodipine | 常州制药厂有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-103383372-B | To gather lead ion sensitive membrane and the Lead Ion-selective Electrode of sulfonation amino anthraquinones as carrier | TONGJI UNIVERSITY (CN) | 2016-05-18 | — | — | CN | disclosed |
| CN-103339117-B | 1,4 oxazines as bace1 and/or bace2 inhibitors | HOFFMANN LA ROCHE | 2015-05-27 | — | — | CN | disclosed |
| CN-103383372-A | Lead ion-sensitive membrane with poly(sulfonated aminoanthraquinone) as carrier and lead ion-selective electrode | UNIV TONGJI | 2013-11-06 | — | — | CN | disclosed |
| CN-103339117-A | 1,4 oxazines as bace1 and/or bace2 inhibitors | HOFFMANN LA ROCHE | 2013-10-02 | — | — | CN | disclosed |
| US-8481327-B2 | Methods for using congeneric, chlorinated, brominated and/or iodised, fluorinated aromatic standard compounds having two benzol rings | CHIRON AS (NO) | 2013-07-09 | — | — | US | disclosed |
| CN-102245181-A | Heterocyclic benzimidazoles as TRPM8 modulators | JANSSEN PHARMACEUTICA NV | 2011-11-16 | — | — | CN | disclosed |
| US-20110229973-A1 | CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF | CHIRON AS (NO) | 2011-09-22 | — | — | US | disclosed |
| US-20070298501-A1 | Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof | CHIRON AS (NO) | 2007-12-27 | — | — | US | disclosed |
| CN-1798740-A | Nitrogen-containing heteroaryl derivatives | GENELABS TECH INC (US) | 2006-07-05 | — | — | CN | disclosed |
| WO-2005077868-A2 | CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF | CHIRON AS (NO) | 2005-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298501-A1 | Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof | CBR1, CYP1A1, CYP1B1 | TSHR 163/4885ORAI1 4666/4885ORAI2 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.