Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30901404 | 1.00 | KMT2A (0.52) | KMT2ANPSR1MEN1GAALMNA | |
| SCHEMBL5539383 | 0.83 | L3MBTL1 (0.48) | KMT2AMEN1GAALMNACA12 | |
| SCHEMBL5754677 | 0.82 | KMT2A (0.55) | KMT2ANPSR1MEN1GAALMNA | |
| SCHEMBL4262591 | 0.82 | KMT2A (0.55) | KMT2ANPSR1MEN1GAALMNA | |
| SCHEMBL26119526 | 0.82 | POLB (0.64) | KMT2ANPSR1MEN1LMNAPOLB | |
| SCHEMBL12937869 | 0.81 | CA12 (0.52) | KMT2ANPSR1MEN1GAALMNA | |
| SCHEMBL15525304 | 0.80 | POLB (0.41) | KMT2ANPSR1MEN1GAALMNA | |
| SCHEMBL3586790 | 0.78 | KMT2A (0.51) | KMT2ANPSR1MEN1GAALMNA | |
| SCHEMBL9379226 | 0.78 | KMT2A (0.51) | KMT2ANPSR1MEN1GAALMNA | |
| SCHEMBL1530222 | 0.78 | L3MBTL1 (0.56) | KMT2ANPSR1MEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294792-A1 | ANTIBACTERIAL COMPOUNDS | Blacksmith Medicines, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| WO-2022173756-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |
| WO-2022173756-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |