SCHEMBL24658996

SCHEMBL24658996

Brc1cccc(-n2c3ccccc3c3cc4c5cccc6c5n(c4cc32)-c2ccccc2-c2ccccc2-6)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
DUSP3 P51452 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
BRD2 P25440 1/20 0.34
MAT2A P31153 1/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
GPR35 Q9HC97 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
DCTPP1 Q9H773 1/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
HPN P05981 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31
PARP1 P09874 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19025084 0.85 KDM4E (0.52) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL24659062 0.84 DUSP3 (0.31) DUSP3
SCHEMBL24659001 0.82 DUSP3 (0.36) KDM4EATML3MBTL1DUSP3MGLL
SCHEMBL17810060 0.81 IDO1 (0.38) DUSP3MEN1KMT2AGSK3BIDO1
SCHEMBL17810053 0.81 IDO1 (0.44) KDM4EATML3MBTL1DUSP3MEN1
SCHEMBL18644405 0.80 L3MBTL1 (0.51) KDM4EATML3MBTL1DUSP3MEN1
SCHEMBL24659013 0.80 DUSP3 (0.36) DUSP3
SCHEMBL17809832 0.79 DUSP3 (0.50) KDM4EATML3MBTL1DUSP3MEN1
SCHEMBL258888 0.79 KDM4E (0.59) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL29514822 0.79 KDM4E (0.59) KDM4EATML3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022199256-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2022-09-29 WO disclosed