Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 20/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 19/20 | 0.43 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23103152 | 0.89 | CD274 (0.47) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL31353950 | 0.89 | CD274 (0.47) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL31354213 | 0.81 | PDCD1 (0.52) | CD274PDCD1 | |
| SCHEMBL23103147 | 0.81 | PDCD1 (0.52) | CD274PDCD1 | |
| SCHEMBL23103161 | 0.79 | CD274 (0.42) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL31004236 | 0.79 | CD274 (0.42) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL24660269 | 0.77 | PDCD1 (0.37) | CD274PDCD1 | |
| SCHEMBL31354292 | 0.76 | PDCD1 (0.43) | CD274PDCD1 | |
| SCHEMBL31004283 | 0.72 | PDCD1 (0.55) | CD274PDCD1 | |
| SCHEMBL31004372 | 0.72 | PDCD1 (0.55) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022166991-A1 | INDOLINE COMPOUND | 南京明德新药研发有限公司 | 2022-08-11 | — | — | WO | disclosed |