SCHEMBL24660269 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	PDCD1	Q15116	14/20	0.37

▸	CD274	Q9NZQ7	14/20	0.37

▸	MAPT	P10636	1/20	0.36

▸	SMN1; SMN2	Q16637	1/20	0.36

▸	KDM4E	B2RXH2	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	SLC6A3	Q01959	2/20	0.35

▸	SLC6A4	P31645	1/20	0.35

▸	LMNA	P02545	1/20	0.34

▸	GAA	P10253	1/20	0.34

▸	TSHR	P16473	1/20	0.34

▸	HTT	P42858	1/20	0.34

▸	LDHA	P00338	1/20	0.34

▸	LDHB	P07195	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31353950	0.85	CD274 (0.47)	PDCD1CD274
SCHEMBL23103152	0.85	CD274 (0.47)	PDCD1CD274
SCHEMBL24660271	0.77	CD274 (0.43)	PDCD1CD274
SCHEMBL20899380	0.72	SLC6A3 (0.43)	PDCD1CD274MAPTKDM4EALDH1A1
SCHEMBL23624231	0.71	NPC1 (0.41)	PDCD1CD274MAPTSMN1; SMN2KDM4E
SCHEMBL22789709	0.71	SLC6A3 (0.44)	PDCD1CD274MAPTKDM4EALDH1A1
SCHEMBL30683763	0.71	SLC6A3 (0.44)	PDCD1CD274MAPTKDM4EALDH1A1
SCHEMBL31279531	0.71	NPSR1 (0.47)	MAPTSMN1; SMN2KDM4EALDH1A1LMNA
SCHEMBL18779093	0.71	NPSR1 (0.47)	MAPTSMN1; SMN2KDM4EALDH1A1LMNA
SCHEMBL22947705	0.70	KDM4E (0.40)	MAPTSMN1; SMN2KDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022166991-A1	INDOLINE COMPOUND	南京明德新药研发有限公司	2022-08-11	—	—	WO	disclosed