SCHEMBL2466074

SCHEMBL2466074

COc1ccc(C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 1.00
RAB9A P51151 3/20 0.67
MAPT P10636 2/20 0.67
KMT2A Q03164 2/20 0.66
MEN1 O00255 1/20 0.66
LMNA P02545 1/20 0.66
MAPK1 P28482 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
RXFP1 Q9HBX9 1/20 0.66
PTGS2 P35354 2/20 0.65
POLB P06746 1/20 0.65
ELANE P08246 1/20 0.61
MAOB P27338 2/20 0.60
MAOA P21397 1/20 0.60
VNN1 O95497 1/20 0.60
ALDH1A1 P00352 1/20 0.59
GAA P10253 1/20 0.59
CES2 O00748 1/20 0.59
CES1 P23141 1/20 0.59
FABP2 P12104 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13250820 0.94 HPGD (0.89) HPGDRAB9AMAPTKMT2AMEN1
SCHEMBL11278329 0.93 HPGD (0.86) HPGDRAB9AMAPTKMT2AMEN1
SCHEMBL2628119 0.89 HPGD (0.80) HPGDRAB9AMAPTKMT2AMEN1
SCHEMBL9418310 0.89 RXFP1 (0.79) HPGDRAB9AMAPTKMT2AMEN1
SCHEMBL51509 0.89 RXFP1 (0.79) HPGDRAB9AMAPTKMT2AMEN1
SCHEMBL9360184 0.86 HPGD (0.76) HPGDRAB9AMAPTKMT2AMEN1
SCHEMBL7722030 0.86 HPGD (0.75) HPGDRAB9AMAPTKMT2AMEN1
SCHEMBL13250807 0.85 HPGD (0.73) HPGDRAB9AMAPTKMT2AMEN1
Acetone SCHEMBL28062673 0.85 HPGD (0.73) HPGDRAB9AMAPTKMT2AMEN1
Ethyne SCHEMBL8195983 0.85 RXFP1 (0.73) HPGDRAB9AMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164442-A Preparation method of 4-chloro-4' -hydroxybenzophenone 杭州臻峰科技有限公司 2023-12-05 CN claimed
CN-114920637-B Preparation process of 4-chloro-4' -hydroxybenzophenone 江苏科技大学 2023-11-21 CN claimed
CN-114920637-A Preparation process of 4-chloro-4' -hydroxybenzophenone 江苏科技大学 2022-08-19 CN claimed
CN-105130795-A Preparation method for high-purity fenofibric acid crude drugs KANGYA OF NINGXIA PHARMACEUTICALS CO LTD 2015-12-09 CN claimed
CN-117164442-A Preparation method of 4-chloro-4' -hydroxybenzophenone 杭州臻峰科技有限公司 2023-12-05 CN disclosed
CN-117164442-A Preparation method of 4-chloro-4' -hydroxybenzophenone 杭州臻峰科技有限公司 2023-12-05 CN disclosed
CN-114920637-B Preparation process of 4-chloro-4' -hydroxybenzophenone 江苏科技大学 2023-11-21 CN disclosed
CN-114920637-B Preparation process of 4-chloro-4' -hydroxybenzophenone 江苏科技大学 2023-11-21 CN disclosed
CN-114920637-A Preparation process of 4-chloro-4' -hydroxybenzophenone 江苏科技大学 2022-08-19 CN disclosed
CN-114920637-A Preparation process of 4-chloro-4' -hydroxybenzophenone 江苏科技大学 2022-08-19 CN disclosed
CN-110483223-B Method for preparing diaryl ketone compound by high-efficiency catalysis of palladium pyridine 陕西师范大学 2022-06-07 CN disclosed
EP-3233799-B1 DOPAMINE D2 RECEPTOR LIGANDS BROAD INST INC (US) 2021-05-19 EP disclosed
EP-1809617-A1 METHOD FOR ACYLATION OF AN AROMATIC COMPOUND Shasun Pharma Solutions Limited (GB) 2007-07-25 EP disclosed
WO-2006048545-A1 METHOD FOR ACYLATION OF AN AROMATIC COMPOUND SHASUN PHARMA SOLUTIONS LIMITED (GB) 2006-05-11 WO disclosed
EP-0934247-A1 PHOTOINITIATORS Lambson Fine Chemicals Limited (GB) 1999-08-11 EP disclosed
WO-1997049664-A1 PHOTOINITIATORS LAMBSON FINE CHEMICALS LIMITED (GB) 1997-12-31 WO disclosed
EP-0172961-B1 1-BUTENE POLYMER AND ITS USE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-19 EP disclosed
EP-0131358-B1 FIRE-RETARDANT 1-BUTENE RESIN COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-08-17 EP disclosed
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed
US-4006243-A FUNGICIDE, BACTERICIDE, YEAST SCHERING AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed