Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 12/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466295 | 0.85 | SCD (0.52) | SCD | |
| SCHEMBL1377431 | 0.84 | SCD (0.66) | SCD | |
| SCHEMBL2466234 | 0.83 | SCD (0.57) | SCD | |
| SCHEMBL2466037 | 0.83 | SCD (0.56) | SCD | |
| SCHEMBL2465681 | 0.82 | SCD (0.51) | SCD | |
| SCHEMBL2470087 | 0.82 | SCD (0.60) | SCD | |
| SCHEMBL2469951 | 0.82 | SCD (0.48) | SCD | |
| SCHEMBL2470127 | 0.81 | SCD (0.53) | SCD | |
| SCHEMBL2469380 | 0.80 | SCD (0.48) | SCD | |
| SCHEMBL2466161 | 0.80 | SCD (0.50) | SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846035-B1 | COMBINATION THERAPY | XENON PHARMACEUTICALS INC (CA) | 2011-09-21 | — | — | EP | claimed |