Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 14/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2472096 | 0.91 | MET (0.56) | MET | |
| SCHEMBL13247059 | 0.89 | MET (0.71) | METNQO2 | |
| SCHEMBL3111915 | 0.85 | MET (0.58) | MET | |
| Hydrochloric Acid SCHEMBL2673060 | 0.84 | HDAC1 (0.58) | MET | |
| SCHEMBL2466985 | 0.84 | MET (0.56) | MET | |
| SCHEMBL15445160 | 0.83 | MET (0.60) | METNQO2 | |
| SCHEMBL2672814 | 0.83 | MET (0.75) | MET | |
| SCHEMBL2468839 | 0.82 | MET (0.60) | MET | |
| SCHEMBL3117528 | 0.82 | MET (0.59) | MET | |
| SCHEMBL2470219 | 0.82 | MET (0.62) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173653-B2 | Pyridiazinone derivatives for the treatment of tumours | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-05-08 | — | — | US | claimed |
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | claimed |