Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24662412 | 0.85 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL22832435 | 0.83 | SLC6A3 (0.58) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL29640045 | 0.83 | SLC6A3 (0.58) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL24661909 | 0.82 | CPN1 (0.49) | — | |
| SCHEMBL4245494 | 0.82 | SLC6A3 (0.61) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7967500 | 0.82 | SLC6A3 (0.63) | SLC6A3 | |
| SCHEMBL13701461 | 0.81 | SLC6A3 (0.61) | SLC6A3 | |
| SCHEMBL13701473 | 0.81 | SLC6A3 (0.61) | SLC6A3 | |
| SCHEMBL27395024 | 0.80 | SLC6A3 (0.57) | SLC6A3 | |
| SCHEMBL30902994 | 0.80 | SLC6A3 (0.62) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221704-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2022-10-20 | — | — | WO | disclosed |