Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
| ▸ | UGT2B17 | O75795 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287385 | 0.91 | UGT2B17 (0.42) | EPAS1UGT2B17CCR1CCR5CCR8 | |
| SCHEMBL22889706 | 0.83 | CYP11B1 (0.37) | EPAS1 | |
| SCHEMBL18629818 | 0.83 | CYP11B1 (0.37) | EPAS1 | |
| SCHEMBL24978275 | 0.79 | CCR1 (0.32) | CCR1CCR5CCR8 | |
| SCHEMBL23782896 | 0.75 | CYP11B1 (0.40) | UGT2B17 | |
| SCHEMBL15883624 | 0.75 | PIM2 (0.35) | — | |
| SCHEMBL13270953 | 0.74 | HTR2A (0.39) | EPAS1UGT2B17CCR1CCR5CCR8 | |
| SCHEMBL10287376 | 0.74 | UGT2B17 (0.37) | EPAS1UGT2B17 | |
| SCHEMBL11519602 | 0.73 | CCR1 (0.31) | CCR1CCR5CCR8 | |
| SCHEMBL10286367 | 0.71 | UGT2B17 (0.38) | EPAS1UGT2B17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022236319-A1 | NAPHTHYRIDONE COMPOUNDS FOR INHIBITION OF RAF KINASES AND/OR BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |