Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287385 | 0.79 | UGT2B17 (0.42) | CCR1CCR5CCR8 | |
| SCHEMBL11522206 | 0.75 | HTR2A (0.35) | CCR1CCR5CCR8 | |
| SCHEMBL24978275 | 0.74 | CCR1 (0.32) | CCR1CCR5CCR8 | |
| SCHEMBL24664867 | 0.73 | EPAS1 (0.37) | CCR1CCR5CCR8 | |
| SCHEMBL11014314 | 0.72 | SIRT1 (0.33) | — | |
| SCHEMBL11519118 | 0.70 | CXCR4 (0.36) | — | |
| SCHEMBL11014315 | 0.69 | SIRT1 (0.31) | — | |
| SCHEMBL26153071 | 0.65 | NPC1 (0.40) | CCR1CCR5CCR8 | |
| SCHEMBL13135358 | 0.65 | CCR1 (0.37) | CCR1CCR5CCR8 | |
| SCHEMBL23782896 | 0.64 | CYP11B1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160094-A | Tetrahydroquinoline derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-07-03 | — | — | US | claimed |
| US-4160094-A | Tetrahydroquinoline derivatives | JOHN WYETH & BROTHER LIMITED (GB) | 1979-07-03 | — | — | US | disclosed |