SCHEMBL24665199

SCHEMBL24665199

OB(O)c1cccc2c1ccc1c3ccccc3oc21

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.44
DYRK1A Q13627 1/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP2C19 P33261 1/20 0.42
MAOA P21397 4/20 0.41
PGR P06401 1/20 0.39
PTGS2 P35354 1/20 0.39
AHR P35869 2/20 0.39
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 1/20 0.38
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
DRD4 P21917 1/20 0.37
KDM5A P29375 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30392062 0.89 ALOX5 (0.46) ALOX5DYRK1AMEN1KMT2ACYP2C19
SCHEMBL8686 0.89 ALOX5 (0.46) ALOX5DYRK1AMEN1KMT2ACYP2C19
SCHEMBL24984709 0.88 ALOX5 (0.43) ALOX5DYRK1AMEN1KMT2ACYP2C19
SCHEMBL29895753 0.87 DYRK1A (0.47) ALOX5DYRK1AMEN1KMT2ACYP2C19
SCHEMBL9110371 0.87 DYRK1A (0.47) ALOX5DYRK1AMEN1KMT2ACYP2C19
SCHEMBL26031852 0.83 ALOX5 (0.57) ALOX5MEN1KMT2ACYP2C19MAOA
SCHEMBL21102639 0.83 ALOX5 (0.56) ALOX5MEN1KMT2ACYP2C19MAOA
SCHEMBL29496940 0.83 ALOX5 (0.56) ALOX5MEN1KMT2ACYP2C19MAOA
SCHEMBL15112991 0.82 ALOX5 (0.44) ALOX5DYRK1AMEN1KMT2ACYP2C19
SCHEMBL16632966 0.81 ALOX5 (0.46) ALOX5DYRK1AMEN1KMT2ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116916672-A Organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2023-10-20 CN disclosed
WO-2022229234-A1 NITROGENOUS HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-11-03 WO disclosed