SCHEMBL24665447

SCHEMBL24665447

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nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.51
ALB P02768 2/20 0.38
FOLH1 Q04609 6/20 0.35
SELP P16109 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
NFKB1 P19838 1/20 0.33
PTGS2 P35354 1/20 0.33
THPO P40225 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NOD1 Q9Y239 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13184723 0.90 GLP1R (0.55) GLP1RFOLH1SELPNOD1
SCHEMBL13184655 0.87 GLP1R (0.53) GLP1RALBFOLH1ALDH1A1KDM4E
SCHEMBL15002746 0.87 GLP1R (0.56) GLP1RALBFOLH1SELPKDM4E
SCHEMBL19261666 0.87 GLP1R (0.53) GLP1RALBFOLH1KDM4EMAPT
SCHEMBL22245420 0.86 GLP1R (0.46) GLP1RFOLH1ALDH1A1
SCHEMBL19704144 0.86 GLP1R (0.46) GLP1RFOLH1ALDH1A1
SCHEMBL19412627 0.85 GLP1R (0.70) GLP1RNOD1
SCHEMBL25462668 0.85 GLP1R (0.49) GLP1RFOLH1ALDH1A1NOD1
SCHEMBL13024568 0.85 GLP1R (0.70) GLP1RNOD1
SCHEMBL25546631 0.85 GLP1R (0.52) GLP1RALBFOLH1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220257779-A1 PROTEIN COMPLEX COMPRISING NON-PEPTIDYL POLYMER-COUPLED FATTY ACID DERIVATIVE COMPOUND AS LINKER AND PREPARATION METHOD THEREFOR HANMI PHARM. CO., LTD. (KR) 2022-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220257779-A1 PROTEIN COMPLEX COMPRISING NON-PEPTIDYL POLYMER-COUPLED FATTY ACID DERIVATIVE COMPOUND AS LINKER AND PREPARATION METHOD THEREFOR FABP1, FABP4, FABP7 GLP1R 463/4885ALB 174/4885FOLH1 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.