SCHEMBL24667243

SCHEMBL24667243

CN1C=CC=NC1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6906143 0.72
SCHEMBL12570744 0.72
SCHEMBL26708456 0.71
SCHEMBL5745252 0.70
SCHEMBL27724806 0.70
SCHEMBL27777052 0.70
SCHEMBL4650148 0.70
SCHEMBL7842864 0.70
SCHEMBL22308091 0.70
SCHEMBL27395449 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022219636-A1 ANTI-VIRAL AND ANTI-TUMORAL COMPOUNDS, AND USES THEREOF YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2022-10-20 WO disclosed
CN-107056693-B A kind of method that high selection prepares N- alkyl pyridine ketone WENZHOU UNIVERSITY (CN) 2019-10-29 CN disclosed
CN-104529884-A Green synthetic method for preparation of N-alkyl pyridone UNIV WENZHOU 2015-04-22 CN disclosed
CN-101857566-B Synthetic method of 2-hydroxypyridine compound ZHEJIANG KEYUAN CHEMICALS CO LTD 2012-09-05 CN disclosed
CN-101857566-A Synthetic method of 2-hydroxypyridine compound ZHEJIANG KEYUAN CHEMICALS CO LTD 2010-10-13 CN disclosed
CN-1108814-C Process for manufacture of pharmaceutical composition containing polyethylene glycol protein conjugates HOFFMANN LA ROCHE (CH) 2003-05-21 CN disclosed
CN-1038035-C Method for preparing polyethylene glycol protein conjugate HOFFMANN LA ROCHE (CH) 1998-04-15 CN disclosed
CN-1175465-A Process for manufacture of pharmaceutical composition containing polyethylene glycol protein conjugates HOFFMANN LA ROCHE (CH) 1998-03-11 CN disclosed
CN-1065465-A Polyethylene glycol protein conjugates HOFFMANN LA ROCHE (CH) 1992-10-21 CN disclosed