⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24667243 | 0.70 | — | — | |
| SCHEMBL27819736 | 0.70 | — | — | |
| SCHEMBL29661265 | 0.70 | — | — | |
| SCHEMBL27395449 | 0.70 | — | — | |
| SCHEMBL7842864 | 0.70 | — | — | |
| SCHEMBL27759171 | 0.69 | — | — | |
| SCHEMBL26708456 | 0.67 | — | — | |
| SCHEMBL27775671 | 0.65 | — | — | |
| SCHEMBL27447017 | 0.65 | — | — | |
| SCHEMBL28120783 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103664764-A | Preparation method of 3-amino-2-hydroxypyridine | CHANGZHOU LEZGUE CHEMICAL CO LTD | 2014-03-26 | — | — | CN | claimed |
| CN-105936635-A | Compound as phosphatidylinositol 3-kinase delta inhibitor and application thereof | 南京圣和药业股份有限公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-105377837-A | N-(heteroaryl)-sulfonamide derivatives useful as S100-inhibitors | ACTIVE BIOTECH AB | 2016-03-02 | — | — | CN | disclosed |
| CN-104045552-A | Medicinal compound as neuroprotective agent | SHANGHAI SIMCERE PHARMACEUTICAL RES CO LTD | 2014-09-17 | — | — | CN | disclosed |
| CN-103709731-A | Quantum dot/polyurethane nano crystal complex and preparation method thereof as well as colorful conversion film | TCL GROUP CO LTD | 2014-04-09 | — | — | CN | disclosed |
| CN-103664764-A | Preparation method of 3-amino-2-hydroxypyridine | CHANGZHOU LEZGUE CHEMICAL CO LTD | 2014-03-26 | — | — | CN | disclosed |
| CN-102858783-A | Thienopyrimidines containing a substituted alkyl group for pharmaceutical compositions | BOEHRINGER INGELHEIM INT | 2013-01-02 | — | — | CN | disclosed |
| CN-102187749-A | Method to form solder deposits on substrates | ATOTECH DEUTSCHLAND GMBH | 2011-09-14 | — | — | CN | disclosed |
| CN-101394830-A | Cosmetic agents comprising purine and/or purine derivatives I | HENKEL KGAA (DE) | 2009-03-25 | — | — | CN | disclosed |
| EP-1651635-A1 | NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS | Pfizer Limited (GB) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005009989-A1 | NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS | PFIZER LIMITED (GB) | 2005-02-03 | — | — | WO | disclosed |
| US-20050020587-A1 | Nicotinamide derivatives useful as PDE4 inhibitors | PFIZER INC | 2005-01-27 | — | — | US | disclosed |
| CN-1238760-A | N- (aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions containing such compounds, and methods of inhibiting beta-amyloid peptide release and or synthesis using such compounds | ELAN PHARM INC (US) | 1999-12-15 | — | — | CN | disclosed |
| CN-1094028-A | Selective PDE enzyme (IV) inhibitor catechol diether class | PFIZER (US) | 1994-10-26 | — | — | CN | disclosed |