Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.38 |
| ▸ | EPOR | P19235 | 4/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24668378 | 0.87 | GLP1R (0.57) | GLP1RFOLH1EPORTLR2SIRT6 | |
| SCHEMBL29328877 | 0.85 | GLP1R (0.58) | GLP1RFOLH1EPORTLR2SIRT6 | |
| SCHEMBL29329023 | 0.83 | GLP1R (0.56) | GLP1RFOLH1EPORTLR2 | |
| SCHEMBL25269707 | 0.81 | GLP1R (0.58) | GLP1RFOLH1EPORSIRT6SIRT1 | |
| SCHEMBL25269706 | 0.81 | GLP1R (0.58) | GLP1RFOLH1EPORSIRT6SIRT1 | |
| SCHEMBL24667764 | 0.78 | GLP1R (0.43) | GLP1RFOLH1TLR2 | |
| SCHEMBL17447162 | 0.78 | CA2 (0.40) | GLP1RFOLH1TLR2MEN1KMT2A | |
| SCHEMBL23158185 | 0.78 | CA2 (0.40) | GLP1RFOLH1TLR2MEN1KMT2A | |
| SCHEMBL30094802 | 0.78 | GLP1R (0.59) | GLP1RTLR2SIRT6SIRT1 | |
| SCHEMBL16328746 | 0.77 | GLP1R (0.51) | GLP1RTLR2SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246086-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-11-24 | — | — | WO | disclosed |