Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | MMP8 | P22894 | 5/20 | 0.53 |
| ▸ | MMP1 | P03956 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 4/20 | 0.53 |
| ▸ | GHSR | Q92847 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 2/20 | 0.47 |
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30096974 | 0.88 | KDM4E (0.52) | MMP2MMP8MMP1MMP9GHSR | |
| SCHEMBL30799784 | 0.87 | GHSR (0.57) | GHSRERAP2 | |
| SCHEMBL31419492 | 0.87 | ACE (0.55) | ACEECE1 | |
| SCHEMBL31259938 | 0.87 | ACE (0.57) | ACEECE1ALOX15 | |
| SCHEMBL31259936 | 0.87 | ACE (0.57) | ACEECE1ALOX15 | |
| SCHEMBL29973876 | 0.87 | ACE (0.57) | ACEECE1ALOX15 | |
| SCHEMBL31259937 | 0.87 | ACE (0.57) | ACEECE1ALOX15 | |
| SCHEMBL31259940 | 0.87 | ACE (0.57) | ACEECE1ALOX15 | |
| SCHEMBL31259935 | 0.87 | ACE (0.57) | ACEECE1ALOX15 | |
| SCHEMBL30628999 | 0.87 | ACE (0.57) | ACEECE1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246086-A1 | ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS | BIOHAVEN THERAPEUTICS LTD. (US) | 2022-11-24 | — | — | WO | disclosed |