SCHEMBL24669059

SCHEMBL24669059

C=CCn1c(=O)n(O)c(=O)n(CC=C)c1=O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.76
NPSR1 Q6W5P4 1/20 0.52
MAPT P10636 1/20 0.42
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
ADORA2B P29275 3/20 0.40
ADORA2A P29274 2/20 0.40
GAA P10253 1/20 0.37
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
PDE4D Q08499 1/20 0.35
USP2 O75604 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
PLA2G4A P47712 2/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28662 0.87 CYP3A4 (1.00) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
Acetone SCHEMBL11800599 0.81 CYP3A4 (0.76) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
SCHEMBL13286724 0.80 CYP3A4 (0.67) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
SCHEMBL24495872 0.80 CYP3A4 (0.67) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
SCHEMBL18368139 0.80 CYP3A4 (0.84) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
SCHEMBL10799429 0.80 CYP3A4 (0.84) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
1,4-Butanediol SCHEMBL11143138 0.79 CYP3A4 (0.73) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
SCHEMBL6263861 0.79 CYP3A4 (0.52) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
SCHEMBL18194710 0.78 CYP3A4 (0.80) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2
SCHEMBL11008643 0.77 CYP3A4 (0.70) CYP3A4NPSR1MAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572469-B2 Resin composition and article made therefrom Elite Material Co., Ltd. (TW) 2023-02-07 US disclosed
US-20220372284-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM Elite Material Co., Ltd. (TW) 2022-11-24 US disclosed