SCHEMBL28662

SCHEMBL28662

C=CCn1c(=O)n(CC=C)c(=O)n(CC=C)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 1.00
NPSR1 Q6W5P4 1/20 0.61
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
ADORA2B P29275 5/20 0.46
ADORA2A P29274 3/20 0.46
MAPT P10636 1/20 0.44
GAA P10253 1/20 0.42
PDE4A P27815 2/20 0.40
PDE4B Q07343 2/20 0.40
PDE4C Q08493 2/20 0.40
PDE4D Q08499 2/20 0.40
USP2 O75604 1/20 0.39
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
ADORA3 P0DMS8 1/20 0.36
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18368139 0.92 CYP3A4 (0.84) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
SCHEMBL10799429 0.92 CYP3A4 (0.84) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
SCHEMBL18194710 0.89 CYP3A4 (0.80) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
SCHEMBL10997976 0.88 CYP3A4 (0.79) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
SCHEMBL24669059 0.87 CYP3A4 (0.76) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
SCHEMBL12218791 0.87 CYP3A4 (0.76) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
SCHEMBL21592085 0.87 CYP3A4 (0.76) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
SCHEMBL20737987 0.87 CYP3A4 (0.76) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
Acetone SCHEMBL11800599 0.87 CYP3A4 (0.76) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2
SCHEMBL16047270 0.87 CYP3A4 (0.76) CYP3A4NPSR1KMT2ASMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 56166 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
EP-4747632-A2 MICROFLUIDIC ENZYME ASSAYS University of Helsinki (FI) 2026-05-27 EP claimed
US-12637618-B2 Method of manufacture of a resin MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-05-26 US claimed
WO-2026101333-A1 HUMAN BODY-IMPLANTABLE INTERFACE HAVING 3D STRUCTURE AND MANUFACTURING METHOD THEREOF 재단법인대구경북과학기술원 2026-05-15 WO claimed
CN-122037272-A Environment-friendly anti-slip antibacterial foam material and preparation method thereof 苏州恒瑞达家用地垫有限公司 2026-05-15 CN claimed
CN-122037595-A Silane polyether-based water-excited cold patch regenerated asphalt material and preparation method thereof 太原理工大学 2026-05-15 CN claimed
CN-122011339-A Special epoxy resin for copper-clad plate with low dielectric loss and synthesis process thereof 铜陵圣创新材料有限公司 2026-05-12 CN claimed
CN-121182168-B Preparation method of stereocomplex polylactic acid 寿光金远东变性淀粉有限公司 2026-05-12 CN claimed
CN-122010121-A Preparation method and application of white carbon black with low water content 鄂尔多斯市蒙泰铝业有限责任公司 2026-05-12 CN claimed
CN-122011508-A Amino-functionalized cubic mesoporous silica composite filler and modified fluororubber 温州大学新材料与产业技术研究院 2026-05-12 CN claimed
US-3979366-A CHAIN EXTENSION CONTINENTAL OIL COMPANY (US) 1976-09-07 US claimed
US-3972847-A PEROXIDES DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-08-03 US claimed
US-3971884-A Ethylene-vinyl acetate silicone rubber adherent laminates and method of production NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1976-07-27 US claimed
US-3971883-A Silicone rubber-ethylene vinyl acetate adhesive laminates and preparation thereof NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1976-07-27 US claimed
US-3965054-A Foamable polyolefin composition and method for manufacturing foamed polyolefin THE FURUKAWA ELECTRIC CO., LTD. (JA) 1976-06-22 US claimed
US-3957916-A CROSSLINKED GRAFT COPOLYMER OF AN ACRYLIC ESTER HITACHI, LTD. (JA) 1976-05-18 US claimed
US-3951926-A TRIALLYL ISOCYANURATE MONSANTO COMPANY (US) 1976-04-20 US claimed
US-3947525-A ETHYLENE-CHLOROTRIFLUOROETHYLENE COPOLYMER ALLIED CHEMICAL CORPORATION (US) 1976-03-30 US claimed
US-3936414-A UNSATURATED MONOMER AND POLYMER, POLYPHENYLENE ETHER, PEROXIDE CATALYST FMC CORPORATION (US) 1976-02-03 US claimed
US-3931346-A Process for preparing a polymerizable diene polymer MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-01-06 US claimed