Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24669277 | 0.89 | HTT (0.38) | KMT2AMEN1ALDH1A1HTTAHR | |
| SCHEMBL24669787 | 0.84 | ALDH1A1 (0.37) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL31636222 | 0.79 | ALDH1A1 (0.36) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL24669230 | 0.79 | ALDH1A1 (0.36) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL13554051 | 0.78 | POLB (0.43) | KMT2AMEN1THRB | |
| SCHEMBL5262113 | 0.77 | MEN1 (0.39) | KMT2AMEN1KDM4EHSD17B10TSHR | |
| SCHEMBL5458213 | 0.76 | KDM6B (0.37) | KMT2AMEN1AHRTHRBNPC1 | |
| SCHEMBL6073419 | 0.76 | MEN1 (0.43) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL661610 | 0.76 | MEN1 (0.38) | KMT2AMEN1ALDH1A1AHRNPC1 | |
| SCHEMBL13345301 | 0.76 | MEN1 (0.38) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |