Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803688 | 1.00 | MAPKAPK2 (0.43) | MAPKAPK2CCNT1CDK9ALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL29803561 | 0.95 | BACE1 (0.41) | MAPKAPK2CCNT1CDK9ALDH1A1L3MBTL1 | |
| SCHEMBL29803320 | 0.92 | MAPKAPK2 (0.52) | MAPKAPK2CCNT1CDK9ALDH1A1L3MBTL1 | |
| SCHEMBL24671574 | 0.92 | MAPKAPK2 (0.52) | MAPKAPK2CCNT1CDK9ALDH1A1L3MBTL1 | |
| SCHEMBL29803656 | 0.89 | MAPKAPK2 (0.49) | MAPKAPK2CCNT1CDK9ALDH1A1L3MBTL1 | |
| SCHEMBL29803700 | 0.89 | USP28 (0.47) | MAPKAPK2ALDH1A1CSF1RSMN1; SMN2HTT | |
| SCHEMBL29803989 | 0.88 | FLT3 (0.48) | MAPKAPK2ALDH1A1CSF1RMAPTMAPK1 | |
| SCHEMBL29803377 | 0.87 | NPC1 (0.46) | MAPKAPK2CSF1RSMN1; SMN2HTTMAPT | |
| Trifluoroacetic Acid SCHEMBL29803660 | 0.86 | USP28 (0.43) | MAPKAPK2ALDH1A1L3MBTL1CSF1RSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29803781 | 0.84 | FLT3 (0.44) | MAPKAPK2ALDH1A1MAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |