Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671471 | 0.84 | CSF1R (0.40) | CSF1RBRPF1MMP2MMP3NAMPT | |
| SCHEMBL29803364 | 0.83 | QDPR (0.42) | CSF1RBTKBRPF1NAMPTCCNT1 | |
| SCHEMBL29802842 | 0.80 | NAMPT (0.52) | WDR5NAMPTCCNT1CDK9 | |
| SCHEMBL24669309 | 0.80 | NAMPT (0.52) | WDR5NAMPTCCNT1CDK9 | |
| Trifluoroacetic Acid SCHEMBL29803809 | 0.80 | P2RY14 (0.40) | CSF1RBTKBRPF1NAMPTCCNT1 | |
| SCHEMBL29803575 | 0.76 | NAMPT (0.40) | MMP2MMP3NAMPTSUCNR1 | |
| SCHEMBL24669304 | 0.76 | CCNT1 (0.47) | CSF1RBTKBRPF1WDR5NAMPT | |
| SCHEMBL29803667 | 0.76 | CCNT1 (0.47) | CSF1RBTKBRPF1WDR5NAMPT | |
| SCHEMBL24670760 | 0.74 | NAMPT (0.45) | HTR1DNAMPT | |
| SCHEMBL29803714 | 0.73 | NAMPT (0.51) | NAMPTCCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |