Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.45 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 1/20 | 0.34 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671576 | 0.85 | NAMPT (0.44) | QDPRNAMPTKDM4E | |
| SCHEMBL29803430 | 0.85 | NAMPT (0.44) | QDPRNAMPTKDM4E | |
| SCHEMBL24670115 | 0.83 | NAMPT (0.43) | QDPRNAMPTGRM5GRM1PRMT5 | |
| SCHEMBL24669354 | 0.82 | NAMPT (0.42) | QDPRNAMPTGRM5GRM1PRMT5 | |
| SCHEMBL29803383 | 0.82 | APOBEC3A (0.41) | QDPRNAMPTGRM5GRM1KDM4E | |
| SCHEMBL24670584 | 0.81 | NAMPT (0.42) | QDPRNAMPTGRM5GRM1PRMT5 | |
| SCHEMBL24669395 | 0.81 | NR1H2 (0.39) | QDPRNAMPTGRM5GRM1KDM4E | |
| SCHEMBL24669924 | 0.81 | NAMPT (0.49) | NAMPTALOX15 | |
| SCHEMBL24670022 | 0.80 | NAMPT (0.42) | QDPRNAMPTGRM5GRM1PRMT5 | |
| SCHEMBL24670320 | 0.80 | NAMPT (0.39) | QDPRNAMPTGRM5GRM1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |