Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.39 |
| ▸ | NPY2R | P49146 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802900 | 1.00 | MAPT (0.43) | MAPTSMN1; SMN2HTTMAPK1KMT2A | |
| SCHEMBL24671018 | 0.92 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2HTTMAPK1KMT2A | |
| SCHEMBL29802868 | 0.90 | CHRM1 (0.42) | MAPTSMN1; SMN2HTTMAPK1KMT2A | |
| SCHEMBL29802911 | 0.90 | TMPRSS2 (0.41) | MAPTSMN1; SMN2HTTMAPK1KMT2A | |
| SCHEMBL29802891 | 0.88 | APOBEC3A (0.49) | MAPTSMN1; SMN2HTTMAPK1KMT2A | |
| SCHEMBL24671336 | 0.88 | TMPRSS2 (0.52) | MAPTSMN1; SMN2RAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL24669288 | 0.85 | NAMPT (0.49) | MAPTSMN1; SMN2HTTMAPK1KMT2A | |
| SCHEMBL29803668 | 0.85 | NAMPT (0.49) | MAPTSMN1; SMN2HTTMAPK1KMT2A | |
| SCHEMBL29803358 | 0.83 | TMPRSS2 (0.47) | MAPTRAB9AAPOBEC3AAPOBEC3GL3MBTL1 | |
| SCHEMBL24671333 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2HTTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |