Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671463 | 0.88 | TMPRSS2 (0.49) | TMPRSS2NPC1RAB9ACHRM1CHRM2 | |
| SCHEMBL29802868 | 0.88 | CHRM1 (0.42) | TMPRSS2NPC1RAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL29802886 | 0.88 | TMPRSS2 (0.49) | TMPRSS2NPC1RAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL29803358 | 0.88 | TMPRSS2 (0.47) | TMPRSS2NPC1RAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL29802900 | 0.88 | MAPT (0.43) | TMPRSS2NPC1RAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL24670017 | 0.88 | MAPT (0.43) | TMPRSS2NPC1RAB9AAPOBEC3AAPOBEC3G | |
| SCHEMBL24671567 | 0.86 | TP53 (0.47) | TMPRSS2MAPTTP53SMN1; SMN2NPY2R | |
| SCHEMBL29802891 | 0.86 | APOBEC3A (0.49) | TMPRSS2RAB9AAPOBEC3AAPOBEC3GCHRM1 | |
| SCHEMBL24671380 | 0.84 | MAPT (0.53) | TMPRSS2NPC1RAB9AMAPTTP53 | |
| SCHEMBL29802911 | 0.84 | TMPRSS2 (0.41) | TMPRSS2NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | claimed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |