Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.49 |
| ▸ | CA2 | P00918 | 11/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 5/20 | 0.49 |
| ▸ | CA7 | P43166 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24670432 | 0.90 | CA1 (0.44) | CA1CA2CA13CA7HTT | |
| SCHEMBL16415327 | 0.83 | CA1 (0.41) | CA1CA2CA13CA7HTT | |
| SCHEMBL2554057 | 0.79 | PPARG (0.51) | CA1CA2CA13CA7HTT | |
| SCHEMBL4712462 | 0.78 | HTT (0.51) | CA1CA2CA13CA7HTT | |
| SCHEMBL24669160 | 0.77 | CA1 (0.52) | CA1CA2CA13CA7HTT | |
| SCHEMBL24669128 | 0.76 | CA1 (0.52) | CA1CA2CA13CA7HTT | |
| SCHEMBL24668699 | 0.76 | CA2 (0.47) | CA1CA2CA13CA7HTT | |
| SCHEMBL24669602 | 0.75 | CA1 (0.51) | CA1CA2CA13CA7HTT | |
| SCHEMBL24670428 | 0.75 | HTT (0.49) | CA1CA2CA13CA7HTT | |
| SCHEMBL24669065 | 0.74 | CA1 (0.43) | CA1CA2CA13CA7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187693-A1 | COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES | UMBRA THERAPEUTICS INC. (US) | 2022-09-09 | — | — | WO | disclosed |